Articles in this Issue

25 articles
1
Research Article

Assessment of Potential Health Hazards Associated with Bacterial Diversity in Municipal Solid Wastes of Okitipupa LGA in Ondo State, Nigeria

Adeyemo I. A*, Demehin A. A.

This study was designed to isolate and characterize the microflora associated with selected solid waste dump sites in Okitipupa Local Government Area (LGA) of Ondo State, Nigeria. Solid waste samples were collected in triplicates from ten (10) dump sites in Okitipupa LGA at two-week interval for three months using a random sampling procedure while culture method is used to isolate the bacteria....

Dec, 2024 pp. 7085-7095
2
Research Article

Extended Spectrum Beta-lactamase Genes in Clinically Important Bacteria Isolated from Wastewater of Two Selected Tertiary Hospitals in Enugu, Nigeria

Agbo O. A.*, Momoh M. A.

Hospital activities have resulted in increased discharge of untreated effluent into the environment, posing substantial risks to public health and the environment due to the presence of diverse harmful components, including extended spectrum β–lactamase (ESBL) producing bacteria harboring resistance genes, which are adding to the global crisis of antimicrobial resistance (AMR). This study aimed...

Dec, 2024 pp. 7096-7103
3
Research Article

Antibiotic Susceptibility Pattern of Bacterial Species Isolated from Selected Underground Water Bodies in Ohaukwu Metropolis, Ebonyi State, Nigeria

Awoke O. O*, Edeh P. A., Ekuma U. O, Ituma M. A, Awoke C. U, Anene C. C, Onwa, N. C

Infections caused by using contaminated water are common in developing nations. Indiscriminate use of antibiotics has led to increased spread of antibiotic-resistance bacteria, even in underground water. This study investigated the susceptibility pattern of bacterial isolates from borehole water and hand-dug wells in Ohaukwu, Ebonyi State, Nigeria. Twenty (20) water samples were collected at r...

Dec, 2024 pp. 7104-7115
4
Research Article

Physicochemical Qualities of Ogbese River, Ovia North East LGA, Edo State, Nigeria

Idemudia I. B.*, Ovenseri A. N, Ekhaise F. O.

Ogbese river is the primary source of drinking water for the community’s inhabitants. It is located in Ogbese town, Ovia North East Local Government Area of Edo State, Nigeria. This study aimed to evaluate the physicochemical parameters which are of public health significance from Ogbese river in Ovia North East Local Government Area of Edo State, Nigeria. Three sampling points, upstream, mids...

Dec, 2024 pp. 7116-7123
5
Research Article

Pathogens Effects of Herbicides (Atrazine, Gramaxone and Glyphosate) on Soil Physicochemical and Microbiological Properties

Jafaru M. I.*, Doughari J. H, Mohammed, A.

The studies on the effects of the herbicide (atrazine, glyphosate and gramaxone) on soil physico- chemical properties was carried out between the months of August 2022 to January2023. Two sites forest and a garden were selected in Federal Polytechnic Mubi, Adamawa State, Nigeria using randomized complete block design (RCBD). The herbicides had significantly increased the amounts of soil organic...

Dec, 2024 pp. 7124-7135
6
Research Article

Screening and Optimization of Biosurfactant Production by Bacillus subtilis from Restaurant Wastewater Contaminated Soil

John W. C.*, Joshua V. I, Ihum T. A., Sikiru G. K, Dinchi P. T., Ishaya M.

Biosurfactant production from Bacillus subtilis RT9(4)B isolated from restaurant wastewater contaminated soil was investigated. The isolated Bacillus subtilis RT9(4)B was screened for biosurfactant production using the emulsification index, oil displacement, zone of haemolysis, surface tension and a positive drop collapse method. Effects of carbon and nitrogen sources, pH, temperature and incub...

Dec, 2024 pp. 7136-7149
7
Research Article

Water Quality Assessment and Antibiotic Susceptibility Testing of Bacteria Isolated from Borehole Water Supplies within a Residential Environment in Elele, Rivers State, Nigeria

Mbah E. I*, Amuchie N. E

Borehole water supplies within residential settings in southern Nigeria are a major source of drinking water for low- and middle-class families. This study was designed to assess the water quality, phenotypic characterization and antibiogram profiling of bacteria isolated from some borehole water supplies within residential environments in Elele, Rivers State, Nigeria, that low and some middle-...

Dec, 2024 pp. 7150-7160
8
Research Article

Microbiological Quality of Sediment and Water Samples from Selected Surface Waters in Anambra State, Nigeria

Okaa A. I.*, Ogu C. T., Chukwujekwu A. G

Water occupies about 70% of the earth’s surface and is one of the most demanded of all urban and rural amenities, thus indispensable for human activities. Microbiological properties of water and sediment samples from four surface waters in Anambra state Nigeria were investigated for the evaluation of their pollution level. A total number of twenty (24) samples, with three (3) samples per sampli...

Dec, 2024 pp. 7161-7166
9
Research Article

Heavy Metals Sludge from Septic Tank Sewage: Implication for Use as Fertilizer

Oyem I. M*, Oyem H. H.

Sludge contains nutrients, heavy metals, and metalloids some of which are essential macronutrients, such as N, P, K, Ca, Mn and other essential trace elements, such as Cu, Fe and Zn. This paper examines the heavy metals within the septic tank system and their eventual accumulation as components of sludge with implication for agricultural use. Sludge samples from the inlet and outlet chambers o...

Dec, 2024 pp. 7167-7173
10
Research Article

Evaluation of Probiotic Properties of Lactic Acid Bacteria Isolated from Some Fermented Foods

Abdulsalam, R.*, Bala, J.D, Abalaka M. E, Ocheme O. B

Probiotics are live microorganisms which when consumed in adequate quantity; promote the health of the consumer. This study was carried out to evaluate probiotic properties of lactic acid bacteria (LAB) isolated from fermented foods (wara, ogi, orange juice, pickles, sauerkraut and grape juice). A total of eighty four isolates were identified as LAB species by morphological, Gram staining and s...

Dec, 2024 pp. 7174-7185
11
Research Article

Detoxification of Poultry Feed Using Candida tropicalis Isolated from Palm Wine

Elesin M. A*, Akinyele B. J, Oluwole, O.R

Aflatoxin contamination in poultry feed poses a significant threat to both poultry health and food safety. This study aimed to explore the potential of using Candida tropicalis, isolated from palm wine, to detoxify aflatoxins in poultry feed ingredients. In this study, Candida tropicalis was isolated from palm wine samples collected within Akure metropolis, Ondo State, Nigeria. The isolated yea...

Dec, 2024 pp. 7186-7195
12
Research Article

Biopreservative Effects of Jack Fruit Seed and Bark on Fruit Juices

Itaman, V.O*, Osaro-Matthew, R. C, Okorie E. E

Fruit juices are drinks consumed worldwide as it contain vitamins, minerals, amino acids, dietary fibers, sugars and bioactive compounds which are important for the wellbeing and health of humans. Fresh fruits are minimally processed to obtain juices which render it perishable products and hence the need to preserve these juices. This study was aimed at investigating the biopreservative potent...

Dec, 2024 pp. 7196-7206
13
Research Article

Profiling Phytochemical Constituents and Antibacterial Efficacy of Ethanol Extract of Anacardium occidentale Linn (Cashew) Slender Branches

Jesse I. A*, Istifanus T., Mafe, A. N, Oloninefa S. D, Attah F, Targema B. T.

Antibiotic resistance in most bacterial infections remains a threat to humanity. This necessitates the search for natural sources of remedy from Anacardium occidentale Linn (cashew) slender branches. The plant slender branches were air dried for four weeks at 25oC and process for extraction. Cold maceration method was used to obtain the extract using ethanol as menstruum. Antibacterial suscepti...

Dec, 2024 pp. 7207-7214
14
Research Article

Evaluation of Fungi Infestation of Stored White and Yellow Cassava Garri in Jos North Metropolis

John W. C*, Ishaya M., Ihum T. A., Joshua V. I, Dinchi P. T., Sikiru G. K

Food security is required national development and for human survival. However, it is important that food security should not be seen only in the perspective of availability but also on safety. This study determined the mycological quality of selected white and yellow Garri sold within Jos North metropolis. The study was conducted at the biology laboratory of Federal College of Forestry, Jos. A...

Dec, 2024 pp. 7215-7225
15
Research Article

Quality Improvement of Watermelon-Clerodendrum volubile Extract Wine Produced via Sequential Malolactic Fermentation by Saccharomyces cerevisiae and Lactobacillus delbrueckii

Kazeem M. O.*, Aderoboye Y. O., Oyinlola K. A, Maiangwa J

Herbal infusions medicinal benefits in wine and the impact of malolactic fermentation on wine quality is of high significance. The study aimed at improving the quality of watermelon wine with Clerodendrum volubile extract using Saccharomyces cerevisiae and Lactobacillus delbrueckii subsp bulgaricus. S. cerevisiae and L. delbrueckii isolated from palm wine and yoghurt, respectively were used in...

Dec, 2024 pp. 7226-7235
16
Research Article

Purification and Characterization of Digitaria exilis Protease (White Acha)

Ogu C. T.*, Mbah N. K, Odibo F. J. C.

The protease of malted Digitaria exilis (white acha) species was extracted, purified and characterized. The enzyme was extracted with 200 ml of 0.1M citrate phosphate buffer (pH 7) containing 0.4% (w/v) cysteine and 0.86% NaCl, purified by dialysis against 4M sucrose, Ion exchange chromatography on CM sepharose and gel filtration chromatography on Sepharose 4B gel. On ion exchange chromatograp...

Dec, 2024 pp. 7236-7242
17
Research Article

Assessment of Lactic Acid Bacteria Treatments on some Biochemical Indices Associated with Ulcerative Colitis Induced in Wistar Rats

Bamigbade B. O.*, Oladejo B. O., Omayone T. P

Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease that affects the colonic mucosa and it’s clinically portrayed by diarrhea, abdominal pain and so on. Lactic acid bacteria (LAB) are one of the most significant groups of probiotic organisms, commonly used in fermented dairy products. These group of organisms enhance lactose digestion, stimulate the immune system, prevent and tr...

Dec, 2024 pp. 7243-7249
18
Research Article

Anti-Bacterial Properties of Leaf Extracts of Moringa olifera and Alchornea cordifolia Against Biofilm-Forming Strains of Pseudomonas aeruginosa

Enya E*, Ekundayo, E. O, Madukwe E. U.

Medicinal plants represent potential sources of new antibacterial agents against drug resistant bacteria. The aim of this study was to investigate the antibacterial activities of aqueous and ethanol extracts of the leaves of Moringa oleifera and Alchornea cordifolia against strains of Pseudomonas aeruginosa expressing various virulence and biofilm-forming characteristics. Five hundred grams (50...

Dec, 2024 pp. 7250-7256
19
Research Article

Multi-Drug Resistance, HIV/AIDS Coinfection and Risk Factors Associated with Mycobacterium tuberculosis Infection in Nigeria: A Systematic Review

Kashibu E*, Doughari J. H, Ja’afaru, M. I.

Multi-drug resistant tuberculosis (MDR-TB) and human immunodeficiency virus (HIV) have emerged as major public health challenges facing tuberculosis control programme particularly in Asia and Africa. In Nigeria, the seroprevalence of HIV is 4.4%, the third highest infection burden in the world, with 21% of all tuberculosis patients dually infected with TB and HIV. The impact of MDR-TB is likely...

Dec, 2024 pp. 7257-7264
20
Research Article

Molecular Detection of Buruli Ulcer among Patients with Various Degrees of Skin Ulcerative Lesions Revealed Zero Prevalence in Parts of Jigawa State, Northern Nigeria

Kashim Y. A.*, Dogara M. M, Mienda B. S., Nwafor T. E, Akinwale O. P, Adeniyi K. A., Abubakar H. H

The indolent, necrotizing Buruli ulcer disease is a chronic condition caused by Mycobacterium ulcerans, an environmental bacteria that can damage the skin, tissues, and bones. It is now recognized as one of the 20 Neglected Tropical Diseases targeted for elimination by the year 2030. Public health continues to face difficulties due to its mechanism of transmission that is yet to be completely u...

Dec, 2024 pp. 7265-7274
21
Research Article

Bacterial Infections of the Upper Respiratory Tract of Different Breeds of Dog in Abeokuta, Ogun State, Nigeria

Lifowora S. O*, Adeyosoye O. I, Akintokun, A. K.

Dogs are domestic animals as well as human pets with potential zoonotic respiratory infections. Nasopharyngeal samples were collected from a total of fifty-five (55) dogs at the Veterinary Teaching Hospital (VTH), Federal University of Agriculture, Abeokuta (FUNAAB), Nigeria. Ten (10) breeds were examined for probable bacteria responsible for upper respiratory tract infection (URTI) and antibio...

Dec, 2024 pp. 7275-7283
22
Research Article

Prevalence of Helicobacter pylori in Nigeria (2010-2023)

Mohammed O. A.*

Helicobacter pylori the aetiologic agent of peptic ulcer, also associated with gastritis and gastric mucosa-associated lymphoid tissue lymphoma, has been reported to be prevalent in some developing countries. Taking into consideration its mode of transmission which is faecal oral, it is important for developing countries to be alert on the nation’s own prevalence, as a high rate could facilitat...

Dec, 2024 pp. 7284-7290
23
Research Article

In-vitro Biofilm Formation and Antimicrobial Resistance of Metallo Beta-lactamase Producing Pseudomonas aeruginosa of Clinical Origin

Nwankwo F. M*, Iroha I. R, Awoke O. A, Ugbo, E. N, Nwankwo L. N

Pseudomonas aeruginosa is an important cause of morbidity and mortality in hospitalized patients and patients with underlying medical conditions. The prevalence of biofilm formation and muti drug resistant strains of P. aeruginosa isolates has been on the increase. This study was aimed at in-vitro biofilm formation in metallo beta-lactamase producing Pseudomonas aeruginosa of clinical origin. A ...

Dec, 2024 pp. 7291-7298
24
Research Article

Occurrence of Metallo-beta-lactamase in Multidrug Resistant Escherichia coli Isolated from Donkey Slaughter Market

Ugbo E. N.*, Ugbo A. I, Agumah B. N, Nwojiji E. C, Ewah C. M, Ogbonna I. P, Ekpono C. U.

Animals used in food production have been identified as one of the major primary sources of antibiotic resistant pathogenic bacteria within the Enterobacteriaceae family. The Escherichia coli harboring metallo-β-lactamases (MBLs) is a serious threat to global health. This study was aimed at the occurrences of metallo-beta-lactamase in multidrug resistance Escherichia coli isolated from donkey ...

Dec, 2024 pp. 7299-7308
25
Research Article

Assessing the Phytochemical Profile and Antimicrobial Efficacy of Allium sativum Against Some Bacterial Pathogens

Unegbu V. N.*, Nwachukwu N. O, Okoronkwo C. U

This research was carried out to examine the phytochemical composition and antibacterial efficacy of garlic against some bacteria pathogens. A standardized phytochemical investigation was done qualitatively utilizing benchmark protocols. The garlic extract’s ability to combat bacterial growth was evaluated using the agar well diffusion assay. Potency of the Allium sativum extracts was investig...

Dec, 2024 pp. 7309-7315